Semen culture, PCR testing for aerobic and anaerobic bacteria, Chlamydia, Mycoplasma, Ureaplasma, CMV, HPV, HSV and other pathogens.

Recent scientific evidence has shown that the composition and balance of the microorganisms naturally present in semen—known as the seminal microbiome—play an important role in sperm function and male fertility.

Microbiological testing of semen is performed either through semen culture or by advanced molecular diagnostic techniques (PCR). These highly sensitive tests detect bacteria, viruses and other pathogens, including Chlamydia, Mycoplasma, Ureaplasma, HPV, CMV and HSV, which may cause infections of the male reproductive tract and adversely affect both fertility and overall male reproductive health.

This comprehensive assessment provides valuable information about the seminal microbiome. When abnormalities are detected, the results help guide personalised treatment strategies, such as targeted antimicrobial therapy or probiotic supplementation, depending on the underlying cause.

Who should consider this test?

Microbiological testing is recommended for all men:

• Who are sexually active and wish to detect asymptomatic genital infections.
• Who want a comprehensive assessment of their fertility.
• Who are planning to conceive.

It is particularly recommended for men who:

• Experience symptoms suggestive of genital tract infection or inflammation (such as pain, swelling, blood in the semen or urinary symptoms).
• Have abnormal semen analysis results.
• Have elevated white blood cell counts in the semen (leukocytospermia).
• Have a history of sexually transmitted infections (STIs).
• Are planning to cryopreserve their sperm.
• Are preparing for assisted reproductive treatment (IUI, IVF or ICSI).
• Are part of a couple experiencing recurrent pregnancy loss.

Benefits of early diagnosis

Early identification and treatment of genital infections can:

• Restore or improve male fertility through appropriate medical treatment.
• Help prevent chronic conditions affecting the male reproductive tract, including chronic prostatitis, epididymitis and other complications.
• Reduce the risk of transmitting infections to a partner and help prevent conditions such as vaginitis, cervicitis, pelvic inflammatory disease and urinary tract infections.
• Improve the chances of successful assisted reproductive treatment.
• Reduce the risk of miscarriage.
• Enhance natural fertility